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Medicines such as Wegovy and Mounjaro are prescription-only

In studies of healthy adults, the portion of oral L-carnitine that is not absorbed is converted to trimethylamine-N-oxide and trimethylamine, metabolites normally excreted by the kidney

In individuals with type 2 diabetes, another phase 2 clinical study demonstrated that after 12 weeks of efinopegdutide treatment, although no significant improvement in glycated hemoglobin (HbA1c) levels was observed, the effect on weight loss reached a high of 7.9%, well above the 0.7% weight reduction rate in the placebo group